Drug intelligence / Profile preview

Belotero Balance + lidocaine

Development stage
Unknown
Lead developer
Merz Aesthetics
Modality
Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intradermal, Submucosal, Subcutaneous
01

Overview

Belotero Balance + lidocaine is a sterile, injectable dermal filler composed of cross-linked hyaluronic acid (22.5 mg/mL) and 0.3% lidocaine hydrochloride in a physiologic phosphate buffer[2][5][6]. The hyaluronic acid is produced by bacterial fermentation (Streptococcus equi), then cross-linked using BDDE via cohesive polydensified matrix (CPM) technology to create a soft, cohesive gel[1][2]. The addition of lidocaine provides local anesthesia to reduce pain during injection[1][4]. It is indicated for the correction of moderate-to-severe facial wrinkles and folds such as nasolabial folds, marionette lines, perioral lines, oral commissures; it is also used for lip enhancement and volume augmentation in the infraorbital hollow in adults over 21 years old[2][6]. The product is administered by injection into the mid-to-deep dermis or submucosal/subcutaneous tissue depending on indication. Developed and manufactured by Merz Aesthetics.

Brand names
Belotero Balance + lidocaineBELOTERO Balance LidocaineBELOTERO BALANCE® (+) Lidocaine
Other names
Belotero Balance with LidocaineBELOTERO BALANCE® (+)
02

Targets

SCN11A (NaV1.9)

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