Drug intelligence / Profile preview

Beltavac

Development stage
Phase 3
Lead developer
Probelte Pharma
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

**Beltavac** is a Probelte Pharma brand of subcutaneous allergen immunotherapy products comprising polymerized allergen extracts, also termed allergoids. The precise active allergen source varies by formulation; documented Beltavac programs include house dust mite extracts and grass-pollen extracts. Repeated subcutaneous administration is intended to induce allergen-specific immune tolerance and reduce symptoms of allergic rhinitis and rhinoconjunctivitis. The house dust mite formulation, containing polymerized extracts from *Dermatophagoides pteronyssinus* and *Dermatophagoides farinae*, is in a Phase III study for allergic rhinitis/rhinoconjunctivitis, while a grass-pollen formulation has been studied in Phase II dose-finding trials. ([ctis.eu](https://ctis.eu/trial/2024-516893-31-01))

Brand names
Beltavac
Other names
house dust mites allergoidpolymerized house dust mite extractdepigmented-polymerized allergenic extract of house dust mites
02

Targets

MHC II (Major histocompatibility complex class II receptor)IgE (Immunoglobulin E)TCR (T cell antigen receptor complex)

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