Drug intelligence / Profile preview

Beltavac polymerized cat dander

Development stage
Unknown
Lead developer
Probelte Pharma
Modality
Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

Beltavac polymerized cat dander is a polymerized (allergoid) extract of cat dander produced by chemical modification with glutaraldehyde. This modification reduces the allergenicity (IgE-binding capacity) while preserving immunogenicity (IgG response), allowing higher and safer dosing for allergen immunotherapy. The extract is characterized by a high Fel d 1 concentration (30 μg/mL) and is adjuvanted with aluminum hydroxide. Beltavac polymerized cat dander is intended for **subcutaneous allergen immunotherapy** in patients with IgE-mediated allergy to cats—mainly allergic rhinoconjunctivitis and asthma—to induce immune tolerance and reduce clinical symptoms. The vaccine is manufactured according to Probeltepharma protocols and is supported by preclinical immunogenicity and clinical safety/effectiveness studies[1][2][3][5][9].

Brand names
Beltavac polymerized cat dander
Other names
Beltavac POLYMERIZED cat danderpolymerized cat dander extractglutaraldehyde-polymerized cat dander
02

Targets

ALB (Human serum albumin)PDX1 (Pancreas/duodenum homeobox protein 1)Feline allergen Fel d 7Feline allergen Fel d 4

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