Drug intelligence / Profile preview

beludavimab

Development stage
Phase 2
Lead developer
Vir Biotechnology
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

Beludavimab (VIR-7832) is an investigational dual-action monoclonal antibody developed for the treatment and prevention of COVID-19. It was designed to target a highly conserved epitope on the spike protein of SARS-CoV-2, which is also shared with SARS-CoV-1, making it less susceptible to resistance from viral mutations. The drug works by inhibiting virus internalization—blocking viral entry into healthy cells—and has been engineered with Fc modifications to enhance its ability to clear infected cells and potentially boost virus-specific T cell responses. Beludavimab was administered as an intravenous infusion in clinical trials and was intended for use in adults with mild-to-moderate COVID-19[3][4][5][6].

Other names
beludavimab
02

Targets

SARS-CoV-2 spike

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