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benactyzine
- Development stage
- Discontinued
- Modality
- Small Molecules
- Administration
- Oral, Intramuscular
01
Overview
Benactyzine is a small molecule anticholinergic drug that was formerly used as an antidepressant for the treatment of depression and associated anxiety. It acts primarily as a muscarinic acetylcholine receptor antagonist and also inhibits nicotinic acetylcholine receptors. Benactyzine was withdrawn from clinical use due to serious side effects such as dry mouth, nausea, and at high doses deliriant or hallucinogenic effects resembling those of mescaline or LSD. It does not possess antihistamine properties. In addition to its psychiatric indications (now discontinued), it has been studied and used in research settings for its antimuscarinic activity and as part of antidote regimens for organophosphate poisoning[1][2][3][4][6].
- Brand names
- SuavitilPhebexPhobexCedadCevanolDeprolLucidilMorcainNutinalParasan
- Other names
- benactyzine
02
Targets
CHRM5 (M5)Nicotinic Acetylcholine Receptor
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