benazepril + hydrochlorothiazide

**Benazepril + hydrochlorothiazide** is an oral fixed-dose antihypertensive combination of benazepril, an angiotensin-converting enzyme inhibitor prodrug, and hydrochlorothiazide, a thiazide diuretic. Hepatic conversion of benazepril to benazeprilat inhibits angiotensin-converting enzyme, reducing angiotensin II formation and aldosterone-mediated vasoconstriction and sodium retention; hydrochlorothiazide inhibits the renal sodium-chloride symporter, increasing sodium and water excretion. The combination is approved for treatment of hypertension and is supplied as oral tablets in multiple strengths. ([pubchem.ncbi.nlm.nih.gov](https://pubchem.ncbi.nlm.nih.gov/compound/Benazepril-hydrochloride-and-hydrochlorothiazide))

Brand names

BriazideCibadrexLotensin HCTZinadiur

Other names

benazepril hydrochloride + hydrochlorothiazidebenazepril HCl + hydrochlorothiazidebenazepril/hydrochlorothiazidehydrochlorothiazide + benazepril