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Bencycloquidium bromide is a novel small molecule anticholinergic drug that acts as a selective muscarinic M1 and M3 receptor antagonist. It is primarily developed for the treatment of allergic rhinitis and related symptoms such as rhinorrhea (runny nose), sneezing, nasal congestion, and itching. The drug is administered intranasally or by inhalation. Its mechanism involves competitively blocking acetylcholine at muscarinic receptors in the nasal mucosa or airways, thereby reducing glandular secretions and smooth muscle spasms associated with allergic responses. Clinical trials have demonstrated its efficacy and safety in patients with persistent allergic rhinitis[1][3][4][6][8]. The developer of bencycloquidium bromide is Yingu Pharmaceutical.
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