Drug intelligence / Profile preview

bendamustine + paclitaxel

Development stage
Phase 1
Lead developer
Teva Pharmaceutical Industries
Modality
Small Molecules
Administration
Intravenous
01

Overview

A combination chemotherapy regimen consisting of bendamustine, an alkylating agent with a benzimidazole ring structure, and paclitaxel, a taxoid antineoplastic agent. This combination leverages complementary mechanisms of action to target cancer cells through DNA damage and microtubule stabilization. It has been studied primarily for metastatic breast cancer treatment.

02

Targets

DNATUBB (Tubulin (alpha and beta subunits))

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