Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
benefiting qi and yin resolving detoxication granule
- Development stage
- Unknown
- Lead developer
- Shanghai Ninth People's Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Benefiting qi and yin resolving detoxication granule (Yiqi Yangyin Jiedu granule) is a Traditional Chinese Medicine (TCM) hospital preparation developed by the Shanghai Ninth People's Hospital affiliated with Shanghai Jiao Tong University School of Medicine. It is specifically indicated for the treatment and prevention of recurrence and metastasis in patients with oral cavity carcinoma, particularly oral squamous cell carcinoma (OSCC). The formulation is based on TCM principles of nourishing Yin, benefiting Qi, and clearing toxic heat to address the underlying pathology of cancer progression. Mechanistically, the granule has been shown to inhibit the epithelial-mesenchymal transition (EMT) of cancer cells, thereby reducing their invasive and migratory potential. Research indicates that it modulates several key oncogenic pathways, including the downregulation of the TGF-β1/Smad signaling axis and the inhibition of the PI3K/Akt pathway, which are critical for tumor growth and metastasis in oral cancer.
- Other names
- Yiqi Yangyin Jiedu granuleYiqi Yangyin Jiedu decoctionYQYYJD
02
Targets
Mitochondrial antiviral-signaling protein–NLR family pyrin domain containing 3–caspase-1 inflammasome axisAKT (RAC-alpha serine/threonine-protein kinase)PI3K (Phosphoinositide-3-kinase regulatory subunit 6)TGFB1 (Transforming growth factor Beta-1 proprotein)
Beyond the preview
Go deeper on benefiting qi and yin resolving detoxication granule.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on benefiting qi and yin resolving detoxication granule.