Drug intelligence / Profile preview

Benfokit

Development stage
Unknown
Lead developer
Learmont Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Benfokit is a commercial generic pharmaceutical product marketed by Learmont Pharmaceuticals, primarily used for the management of diabetic neuropathy and other nerve-related conditions. It is a combination formulation that features benfotiamine, a lipid-soluble derivative of thiamine (vitamin B1) with high bioavailability. Benfotiamine works by activating the enzyme transketolase, which helps divert excess glucose metabolites into safer pathways, thereby reducing the formation of advanced glycation end-products (AGEs) that damage nerves and blood vessels. The product also contains alpha-lipoic acid, a potent antioxidant that neutralizes reactive oxygen species, and neurotropic B-vitamins such as methylcobalamin (vitamin B12), pyridoxine (vitamin B6), and folic acid, which support myelin sheath synthesis and nerve fiber regeneration.

Brand names
Benfokit
02

Targets

TKT (Transketolase)MTR (Methionine synthase)

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