Drug intelligence / Profile preview

benfotiamine + mecobalamin + alpha-lipoic acid + folic acid + pyridoxine

Development stage
Unknown
Lead developer
Solis Pharms
Modality
Small Molecules
Administration
Oral
01

Overview

Bentab Plus is an oral fixed-dose combination formulation developed by Solis Pharms, containing benfotiamine (100 mg), mecobalamin (1500 mcg), alpha-lipoic acid (100 mg), folic acid (1.5 mg), and pyridoxine (3 mg). It is primarily indicated for the management of diabetic peripheral neuropathy and other neuropathic conditions. Benfotiamine, a lipid-soluble derivative of thiamine, helps prevent vascular damage by activating the enzyme transketolase and reducing the formation of advanced glycation end-products (AGEs). Mecobalamin, the active form of vitamin B12, promotes nerve regeneration and myelin sheath formation. Alpha-lipoic acid serves as a potent antioxidant that improves endoneurial blood flow and reduces oxidative stress. Folic acid and pyridoxine provide essential cofactors for neurotransmitter synthesis and homocysteine metabolism, further supporting nerve health and function.

Brand names
Bentab Plus
Other names
Benfotiamine 100mg, Mecobalamin 1500mcg, ALA 100mg, Folic Acid 1.5mg & Pyridoxine 3mg TabletsBentab Plus-Solis Pharms-small molecule-oral
02

Targets

MTR (Methionine synthase)TKT (Transketolase)

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