Drug intelligence / Profile preview

benmoxin

Development stage
Discontinued
Modality
Small Molecules
Administration
Oral
01

Overview

Benmoxin is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class. It was first synthesized in 1967 and was used as an antidepressant in Europe, but it is no longer marketed. As a nonselective MAOI, benmoxin inhibits both MAO-A and MAO-B enzymes, leading to increased levels of monoamine neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This mechanism underlies its antidepressant effects[1][2][3][4][8].

Brand names
NeuralexNerusil
Other names
mebamoxine
02

Targets

MAOB (Monoamine oxidase B)MAOA (Monoamine oxidase A)

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