Drug intelligence / Profile preview

benzocaine (Bee Brand Medico Dental)

Development stage
Unknown
Lead developer
Bee Brand Medico Dental
Modality
Small Molecules
Administration
Topical
01

Overview

BEEZOCAINE Dental Jelly (ビーゾカイン歯科用ゼリー) is a topical surface anesthetic gel developed and manufactured by Bee Brand Medico Dental in Japan. It contains 20% benzocaine (ethyl aminobenzoate) as its active pharmaceutical ingredient. The gel is formulated for dental applications, such as reducing pain during local anesthetic injections (needle insertion), scaling, and gingival retraction. Benzocaine acts as a local anesthetic by reversibly binding to and blocking voltage-gated sodium channels in nerve membranes, thereby inhibiting sodium ion influx, preventing depolarization, and blocking nerve impulse conduction. BEEZOCAINE Dental Jelly is characterized by its rapid onset of action (approximately 30 seconds) and a short, appropriate duration of effect (approximately 5 minutes), and it is flavored with a banana aroma to improve patient compliance, particularly in pediatric dentistry.

Brand names
BEEZOCAINE Dental Jellyビーゾカイン歯科用ゼリービーゾカイン歯科用ゼリー20%
Other names
ethyl 4-aminobenzoateethyl4-aminobenzoateethyl-4-aminobenzoateethyl aminobenzoateアミノ安息香酸エチル
02

Targets

NaV alpha (Voltage-gated sodium channel alpha subunit family)

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