Drug intelligence / Profile preview

benzododecinium

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Ophthalmic
01

Overview

Benzododecinium is a quaternary ammonium compound used primarily as an antiseptic and disinfectant. It acts as a cationic surfactant, disrupting microbial cell membranes, which leads to leakage of cellular contents and cell death. Benzododecinium is effective against gram-positive bacteria and has variable activity against some gram-negative organisms; it is not effective against Mycobacterium tuberculosis or bacterial spores. It is also used as a preservative in pharmaceutical formulations, including ophthalmic solutions, where it can enhance corneal permeability. The drug has been marketed in the Czech Republic under the brand name Ajatin for wound antisepsis[1][2][4][8].

Brand names
AjatinSterinol
Other names
benzododecinium bromidebenzododecinium chloridebenzyldimethyldodecylammonium bromidebenzyldimethyldodecylammonium chloridedodecyldimethylbenzylammonium chloride

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