Drug intelligence / Profile preview

benzoin resin

Development stage
Unknown
Administration
Topical, Inhalation, Oral
01

Overview

Benzoin resin is a natural balsamic resin obtained from the bark of several species of trees in the genus *Styrax*, primarily *Styrax benzoin* and *Styrax tonkinensis*. It is produced as a pathologic exudate in response to bark injury. The resin is chemically complex, containing balsamic acid esters (such as benzyl benzoate), benzoic acid, cinnamic acid, and various triterpenoids. Historically used as incense and a flavoring agent, it has significant therapeutic applications as a topical antiseptic and protectant. It is commonly formulated as Compound Benzoin Tincture to treat minor skin irritations, wounds, and ulcers. Additionally, its fumes are used traditionally for respiratory relief and in religious ceremonies. Modern research has identified its potential as an antibacterial, antifungal, and antioxidant agent, with specific inhibitory activities against enzymes like alpha-glucosidase and bacterial targets such as dihydrofolate reductase.

Brand names
Compound Benzoin Tincture
Other names
gum benzoinSumatra benzoinSiam benzoinJawi OudStyrax resinbenzoinumsemipetrified amberStyrax benzoinStyrax tonkinensisStyrax sumatranaStyrax japonicus
02

Targets

IleRS (Isoleucyl-tRNA synthetase)Sucrase-IsomaltaseDHFR (Dihydrofolate reductase)DHPS (Dihydropteroate synthase)

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