Drug intelligence / Profile preview

benzylpenicillin sodium

Development stage
Approved
Lead developer
Pirkanmaan hyvinvointialue
Modality
Small Molecules
Administration
Intravenous, Intramuscular
01

Overview

Benzylpenicillin sodium is the sodium salt formulation of **benzylpenicillin (penicillin G)**, a natural beta-lactam penicillin antibiotic used to treat susceptible **bacterial infections**. It acts by binding penicillin-binding proteins and inhibiting the transpeptidation step of **bacterial peptidoglycan cell-wall synthesis**, leading to loss of cell-wall integrity and bactericidal activity in actively dividing organisms. The drug has historically been developed and commercialized by multiple manufacturers rather than a single originator-focused biotech program, is typically supplied as a powder for reconstitution for parenteral use, and remains an established therapy for serious infections caused by susceptible streptococci, pneumococci, meningococci, clostridia, treponemes, and other penicillin-sensitive bacteria.

Brand names
CrystapenPfizerpen
Other names
penicillin G sodiumsodium benzylpenicillinbenzylpenicillin sodium salt
02

Targets

PBP (Penicillin-binding protein family)

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