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Benzylpenicillin sodium is the sodium salt formulation of **benzylpenicillin (penicillin G)**, a natural beta-lactam penicillin antibiotic used to treat susceptible **bacterial infections**. It acts by binding penicillin-binding proteins and inhibiting the transpeptidation step of **bacterial peptidoglycan cell-wall synthesis**, leading to loss of cell-wall integrity and bactericidal activity in actively dividing organisms. The drug has historically been developed and commercialized by multiple manufacturers rather than a single originator-focused biotech program, is typically supplied as a powder for reconstitution for parenteral use, and remains an established therapy for serious infections caused by susceptible streptococci, pneumococci, meningococci, clostridia, treponemes, and other penicillin-sensitive bacteria.
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