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bepotastine besilate
- Development stage
- Approved
- Lead developer
- Bausch + Lomb
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
Bepirex is an ophthalmic solution containing bepotastine besilate (1.5% w/v), a second-generation antihistamine and mast cell stabilizer. It is developed by Zivira Labs and is approved for the treatment of ocular itching associated with allergic conjunctivitis. Bepotastine besilate acts as a highly selective antagonist of the histamine H1 receptor, inhibits the release of histamine from mast cells, and suppresses eosinophil migration into inflamed tissues, thereby providing rapid and long-lasting relief from allergic eye symptoms.
- Brand names
- AllerbepBepirexBepixBepobesilBepochekBepofreeBepogardBepolineBepotineBepotosinBepreveBeposwissBepotimeBetsharpBipodineBrpotineOptihist BangRadipat GoldRotobepTalion
- Other names
- bepotastinebepotastine benzenesulfonatebepotastine besilatebepotastine besylatebetotastinebetotastine besilate
02
Targets
σR (Sigma receptors)HRH1 (Histamine H1 Receptor)
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