Drug intelligence / Profile preview

berberine + vitamin B12 + magnesium citrate + cinnamon bark + chromium

Development stage
Unknown
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral
01

Overview

A multi-ingredient **dietary supplement** composed of berberine, vitamin B12, magnesium citrate, cinnamon bark, and chromium, formulated primarily for metabolic health and blood glucose support. Berberine is a plant-derived alkaloid known to activate AMP-activated protein kinase (AMPK), which supports glucose and lipid metabolism. Vitamin B12 is an essential water-soluble vitamin involved in nerve function and red blood cell formation. Magnesium citrate is a bioavailable source of magnesium, essential for enzymatic, muscle, and nerve functions, and may improve insulin sensitivity. Cinnamon bark, rich in polyphenols, may lower fasting blood glucose and improve lipid profiles, possibly by increasing insulin sensitivity through multiple pathways. Chromium is a trace mineral involved in enhancing insulin action and supporting glucose metabolism. The combination has been evaluated in clinical trials indicating improved glycemic parameters in patients with type 2 diabetes. Typical use is as an oral supplement, often in capsule or gummy form, from a variety of dietary supplement manufacturers, with main indications including blood glucose regulation and metabolic health[1][3][4][5][6].

02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)

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