berberine tannate

Berberine tannate is a salt form of the isoquinoline alkaloid berberine, combined with tannic acid. It is primarily utilized as an active pharmaceutical ingredient (API) in the treatment of gastrointestinal disorders, particularly diarrhea and gastroenteritis. The tannate salt form is often preferred in oral formulations to mitigate the intense bitterness of berberine and potentially provide a more controlled release within the digestive tract. Berberine itself exhibits a broad spectrum of biological activities, including antimicrobial, anti-inflammatory, and metabolic regulatory effects, often attributed to its ability to activate adenosine monophosphate-activated protein kinase (AMPK) and interact with DNA and RNA. Inga Pharmaceuticals is a notable manufacturer of this bulk ingredient.

Other names

berberine tannateberberine, salt with tannic acid