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Best CLEANSE Forever
- Development stage
- Unknown
- Lead developer
- DERMALA
- Modality
- Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Topical
01
Overview
Best CLEANSE Forever is a topical probiotic acne cleanser developed by DERMALA that targets the skin microbiome to manage acne. The formulation features the patented SE Microbiome Complex®, a proprietary blend of prebiotics and postbiotics derived from *Staphylococcus epidermidis*. It works by selectively inhibiting acne-causing bacteria (*Cutibacterium acnes*) while promoting the growth of beneficial skin bacteria to restore a healthy cutaneous microbiota balance. The cleanser is designed with a slightly acidic pH of approximately 5.5 to support the skin's natural barrier and includes natural plant extracts and amino acids to cleanse without over-drying. It is marketed as an FDA-approved treatment for acne, representing a novel microbiome-based modality in the consumer skincare space.
- Brand names
- Best CLEANSE ForeverBest CLEANSE Forever Probiotic Acne Cleanser
- Other names
- DERMALA topical probiotic acne cleanserSE Microbiome Complex cleanser
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