beta-hydroxy-beta-methylbutyrate + adenosine triphosphate

This is a **combination dietary supplement** of **beta-hydroxy-beta-methylbutyrate (HMB)**, a metabolite of leucine, and **adenosine triphosphate (ATP)**, the primary energy carrier molecule in cells. HMB is commonly used to **support muscle health** by stimulating muscle protein synthesis (primarily via mTOR pathway activation [1][3][4]) and inhibiting muscle protein breakdown, including via ubiquitin-proteasome and autophagic-lysosomal systems[1]. ATP supplementation may enhance muscle performance and training adaptations by directly supporting muscle energy availability[2]. In clinical studies, this **combination has shown additive and synergistic effects**, leading to **increased lean body mass, strength, and power in trained individuals**, particularly during periods of high physical stress or overreaching[2]. Effects on recovery, reduced muscle damage, improved aerobic and anaerobic capacity, and attenuation of strength decline under fatigue have also been observed[2][4]. The combination is not classified as a pharmaceutical, but rather as a sports nutrition product.

Other names

HMB + ATPbeta-hydroxy-beta-methylbutyrate and adenosine triphosphateHMB-FA + ATPHMB free acid + ATP