betamethasone dipropionate + betamethasone sodium phosphate + ropivacaine

This combination treatment regimen consists of **Diprospan** (a dual-action corticosteroid formulation combining quick-acting betamethasone sodium phosphate and long-acting betamethasone dipropionate) and **ropivacaine** (a long-acting local anesthetic). It is used for pre-emptive scalp infiltration to manage postoperative pain and post-craniotomy headache in patients undergoing elective craniotomy. The biological mechanism involves a synergistic approach: ropivacaine provides immediate and prolonged nerve conduction blockade at the surgical site, while the corticosteroid components of Diprospan exert anti-inflammatory effects that prevent the liberation of inflammatory mediators around the incision. This investigational protocol is being evaluated by **Beijing Tiantan Hospital** (Capital Medical University) to reduce opioid consumption and improve pain scores in both adult and pediatric populations.

Brand names

Diprospan + ropivacaine

Other names

Diprospan plus ropivacainethe r group-Beijing Tiantan Hospital-postoperative pain-post-craniotomy headache