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betamethasone dipropionate + miconazole nitrate + neomycin sulfate
- Development stage
- Unknown
- Lead developer
- Ancalima Lifesciences
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Betaderm MN Cream is a topical combination dermatological formulation containing betamethasone dipropionate (a potent corticosteroid), miconazole nitrate (an imidazole antifungal), and neomycin sulfate (an aminoglycoside antibiotic). It is developed by Ancalima Lifescience and is indicated for the treatment of inflammatory skin conditions (such as eczema, psoriasis, and dermatitis) complicated by secondary bacterial and/or fungal infections. Betamethasone dipropionate acts as an anti-inflammatory and antipruritic agent by binding to glucocorticoid receptors. Miconazole nitrate targets fungal cell membrane synthesis by inhibiting lanosterol 14-alpha-demethylase, and neomycin sulfate inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.
- Brand names
- Betaderm MNBetaderm MN Cream
- Other names
- betamethasone dipropionate + miconazole nitrate + neomycin sulphate
02
Targets
30S A-site (Bacterial ribosomal 30S A-site)GR (Glucocorticoid receptor)CYP51A1 (Sterol 14α-demethylase)
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