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Drug intelligence / Profile preview
betamethasone sodium phosphate + betamethasone acetate
- Development stage
- Approved
- Lead developer
- Organon
- Modality
- Small Molecules
- Administration
- Intramuscular, Intraarticular, Intralesional
01
Overview
Betamethasone sodium phosphate + betamethasone acetate is a fixed-dose injectable suspension containing two ester forms of the synthetic glucocorticoid betamethasone. The water-soluble sodium phosphate ester provides relatively prompt systemic glucocorticoid activity, while the sparingly soluble acetate ester provides a depot effect and more sustained exposure. It is used as an anti-inflammatory, antiallergic, and immunosuppressive corticosteroid preparation for corticosteroid-responsive conditions, including selected allergic, dermatologic, rheumatic, musculoskeletal, hematologic, neurologic, renal, respiratory, ophthalmic, and gastrointestinal disorders. The combination is also administered locally by intra-articular, soft-tissue, or intralesional injection for inflammatory joint, tendon, and dermatologic lesions.
- Brand names
- Celestone SoluspanRinderon for Suspended Injection
- Other names
- betamethasone acetate + betamethasone sodium phosphatebetamethasone acetate/betamethasone sodium phosphatebetamethasone sodium phosphate and betamethasone acetatebetamethasone sodium phosphate/betamethasone acetate
02
Targets
GR (Glucocorticoid receptor)
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