betamethasone sodium phosphate + triamcinolone acetate

This drug entry refers to a specific glucocorticoid combination therapy protocol utilized by the Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University for the treatment of erosive oral lichen planus (OLP). The regimen consists of local blockade therapy using **betamethasone sodium phosphate** injection and the topical application of **triamcinolone acetate** ointment (typically 1%). These synthetic corticosteroids function as potent agonists of the glucocorticoid receptor, exerting significant anti-inflammatory and immunosuppressive effects by modulating gene expression and inhibiting the T-cell mediated chronic inflammatory response characteristic of OLP. In clinical trial settings, this combination is often evaluated in conjunction with periodontal initial treatment to enhance mucosal healing, reduce the size of erosive lesions, and alleviate patient discomfort. The protocol may also include supportive measures such as sodium bicarbonate rinses to maintain oral pH and prevent secondary fungal infections.

Other names

glucocorticoid-Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityGlucocorticoid Therapy (Shanghai Ninth People's Hospital)Betamethasone and Triamcinolone combination