Drug intelligence / Profile preview

betamethasone valerate

Development stage
Phase 3
Lead developer
IBSA
Modality
Small Molecules
Administration
Topical, Transdermal
01

Overview

IBSA BMV (brand name: Betesil) is a ready-to-use, self-adhering medicated plaster containing 0.1% betamethasone 17-valerate (BMV), developed by IBSA Institut Biochimique. It is designed for the localized, occlusive treatment of steroid-responsive inflammatory dermatoses, such as chronic plaque psoriasis, eczema, lichen planus, and granuloma annulare. By delivering betamethasone valerate—a medium-to-high potency synthetic corticosteroid—transdermally, the plaster acts as a glucocorticoid receptor agonist to exert anti-inflammatory, immunosuppressive, antiproliferative, and vasoconstrictive effects. The occlusive nature of the plaster also enhances skin hydration and drug penetration while protecting the affected area from mechanical trauma.

Brand names
BetesilBeteflamBetasil
Other names
betamethasone valerate medicated plasterbetamethasone valerate patchbetamethasone 17-valerate medicated plasterbetamethasone17-valerate medicated plasterbetamethasone-17-valerate medicated plasterIBSA Tape
02

Targets

GR (Glucocorticoid receptor)MR (Mineralocorticoid receptor)PR (Progesterone receptor)

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