Drug intelligence / Profile preview

bethanecol + omeprazole

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Intravenous, Subcutaneous
01

Overview

This is a combination of two pharmaceutical drugs, bethanechol and omeprazole. Bethanechol is a cholinergic agonist that stimulates muscarinic receptors, primarily used to treat urinary retention by increasing bladder muscle tone and promoting urination. It may also be used for certain gastrointestinal conditions such as gastroparesis or postoperative ileus due to its prokinetic effects[3][4][5]. Omeprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, commonly indicated for gastroesophageal reflux disease (GERD), peptic ulcer disease, and other acid-related disorders[6]. There are no known fixed-dose combination products containing both drugs; this entry refers to their concurrent use.

02

Targets

ATP4A (Potassium–transporting ATPase alpha chain 1)mAChR (Muscarinic acetylcholine receptors)ATP1A1 (Sodium/potassium-transporting ATPase subunit alpha-1)

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