Drug intelligence / Profile preview

BETIC

Development stage
Unknown
Lead developer
Learmont Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

BETIC is a brand of betahistine dihydrochloride, a generic pharmaceutical product distributed by Learmont Pharmaceuticals. Betahistine is a histamine analogue primarily indicated for the symptomatic treatment of Ménière's disease and vestibular vertigo. Its pharmacological action is characterized by potent antagonism at histamine H3 receptors and weak agonism at histamine H1 receptors. By antagonizing H3 receptors, BETIC increases the release of neurotransmitters such as histamine and acetylcholine in the inner ear, which improves microcirculation in the stria vascularis. Additionally, its H1 agonism promotes local vasodilation. These combined effects help to reduce endolymphatic pressure and modulate the activity of vestibular nuclei, thereby alleviating symptoms such as dizziness, tinnitus, and hearing loss.

Brand names
BETICBETIC-8BETIC8BETIC 8BETIC-16BETIC16BETIC 16
Other names
betahistine dihydrochloride
02

Targets

HRH3 (Histamine Receptor H3)HRH1 (Histamine H1 Receptor)

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