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BG-301

Development stage: Preclinical
Lead developer: BlissGene Therapeutics
Modality: Gene Therapies

Overview

BG-301 is an investigational gene therapy being developed by BlissGene Therapeutics for the treatment of major depression. Currently in the discovery stage, the therapeutic is designed to modulate gene expression within the prefrontal cortex and hippocampus, two brain regions that play a central role in mood regulation and the pathophysiology of depressive disorders. By utilizing a gene therapy modality, BG-301 aims to address the underlying molecular mechanisms of depression, potentially offering a novel approach to managing treatment-resistant or severe cases of the disease.

Targets

PABPN1 (Polyadenylate-binding nuclear protein 1)

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