Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
BG505 MD39.3 gp151 CD4KO mRNA
- Development stage
- Phase 1
- Lead developer
- Scripps Research
- Modality
- mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
BG505 MD39.3 gp151 CD4KO mRNA is an experimental HIV vaccine candidate based on messenger RNA (mRNA) technology. It is designed to present the spike protein found on the surface of HIV that facilitates entry into human cells. This vaccine encodes for stabilized HIV envelope trimers that aim to elicit autologous neutralizing antibodies. The vaccine works by delivering genetic material that instructs the body to make a protein fragment of HIV, which the immune system recognizes and remembers, allowing it to mount a substantial response if later exposed to the virus. The vaccine cannot cause HIV infection.
02
Targets
BCR-HIV-Env (HIV-1 envelope-specific B-cell receptor)CD4 (T lymphocyte surface antigen)
Beyond the preview
Go deeper on BG505 MD39.3 gp151 CD4KO mRNA.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on BG505 MD39.3 gp151 CD4KO mRNA.