Drug intelligence / Profile preview

BGM1812

Development stage
Phase 1
Lead developer
BrightGene Bio-Medical Technology
Modality
Peptides, Small Molecules
Administration
Subcutaneous
01

Overview

BGM1812 is a long-acting amylin analog under development for metabolic diseases. Amylin is a 37-amino acid peptide hormone co-secreted with insulin by pancreatic beta cells. It plays a role in glycemic control by inhibiting gastric emptying and controlling appetite, which leads to both hypoglycemic and weight loss effects. BGM1812 aims to leverage these properties for the treatment of diabetes and potentially obesity. The drug is being developed as part of an innovative approach to metabolic disease management, where combination regimens (such as pairing amylin analogs with GLP-1 receptor agonists) are increasingly explored for synergistic benefits in blood sugar control and weight reduction[4][1].

02

Targets

AMY receptor (Calcitonin receptor (with ramps))CALCR (Calcitonin receptor)

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