Drug intelligence / Profile preview

BH006

Development stage
Phase 1
Lead developer
Zhuhai Beihai Biotech
Modality
Small Molecules
Administration
Intravenous
01

Overview

**BH006** is an investigational intravenous fixed-dose antiemetic combination developed by Zhuhai Beihai Biotech for prevention of chemotherapy-induced nausea and vomiting. The injection combines **fosaprepitant**, an intravenous prodrug of the neurokinin 1 receptor antagonist aprepitant, with **palonosetron**, a long-acting serotonin 5-hydroxytryptamine 3 receptor antagonist. Its intended regimen has been studied against separately administered fosaprepitant and palonosetron in healthy-subject relative-bioavailability trials.

Other names
BH006BH-006BH 006
02

Targets

HTR3A (5-hydroxytryptamine receptor 3A)TACR1 (Neurokinin‑1 Receptor)

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