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Bharat Biotech's HPV vaccine is a prophylactic vaccine candidate designed to prevent infections caused by the Human Papillomavirus (HPV) and associated diseases, such as cervical cancer and other HPV-associated malignancies. The company's research has explored various technological platforms, including Virus-Like Particles (VLPs) based on the L1 capsid protein and a chimeric L2-based approach. Specifically, one strategy involved the expression of an L2-HBV small surface antigen fusion protein in the yeast *Pichia pastoris* to generate VLPs. The vaccine is intended to elicit a robust immune response, producing neutralizing antibodies that protect against viral infection and the subsequent development of HPV-related lesions.
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