Drug intelligence / Profile preview

BI 1060469 TF2

Development stage
Unknown
Lead developer
Boehringer
Modality
Small Molecules
Administration
Oral
01

Overview

**BI 1060469 TF2** is a *tablet formulation* of the small molecule drug BI 1060469, developed by Boehringer Ingelheim. BI 1060469 acts as a selective antagonist of **CRTH2 (Prostaglandin D2 receptor 2)**, blocking the effects of prostaglandin D2 (PGD2) in inflammatory pathways[1]. This mechanism is being explored for the treatment of immune system and respiratory diseases, primarily asthma. The "TF2" designation refers to a specific oral tablet formulation, distinguished from earlier prototypes (e.g., TF1), with clinical trials focused on its pharmacokinetics and bioavailability in healthy subjects[2][3][4].

Other names
BI-1060469 TF2BI1060469 TF2BI 1060469 TF2BI 1060469 + TF2
02

Targets

PTGDR2 (Prostaglandin D2 receptor 2)

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