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Biejia Ruangan Jianpi Decoction is a traditional Chinese medicine (TCM) herbal formula used primarily for the treatment of chronic liver diseases such as hepatic fibrosis and cirrhosis. It is a multi-herb combination designed to "soften hardness," "dissolve stasis," and "strengthen the spleen" according to TCM theory. The decoction typically contains ingredients such as turtle shell (Biejia), various herbs that invigorate blood circulation, resolve stasis, and support digestive function ("Jianpi"). Modern research indicates that this formula exerts anti-fibrotic effects by targeting multiple pathways involved in liver fibrosis progression. Mechanistically, it may inhibit hepatic stellate cell activation, modulate immune responses, reduce inflammation and oxidative stress in the liver microenvironment. Clinical studies have shown its use—often in combination with antiviral agents like entecavir or ursodeoxycholic acid—can improve biochemical indices of liver function and reduce risk of hepatocellular carcinoma in patients with chronic hepatitis B or primary biliary cholangitis[2][3]. The product is available as a Chinese patent medicine under names like Fufang Biejia Ruangan tablets (FFBJRG), which has been approved by regulatory authorities in China for anti-fibrosis therapy[3].
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