Drug intelligence / Profile preview

bifidobacteria-fermented milk

Development stage: Unknown
Lead developer: Yakult Honsha
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

Bifidobacteria-fermented milk (BFM) is a dietary supplement that acts as a probiotic, containing beneficial bifidobacteria. It is being investigated as a dietary adjunct for the treatment and maintenance of remission in ulcerative colitis. Its mechanism involves modulating the intestinal flora, specifically reducing the relative proportion of harmful bacteria like *Bacteroides vulgatus* and increasing the concentration of beneficial short-chain fatty acids such as butyrate and propionate in the feces. This modulation of the gut microbiome contributes to its therapeutic effects in inflammatory bowel conditions.

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