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Bifidobacterium animalis subsp. lactis BLC1

Development stage
Unknown
Lead developer
Saccoo
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bifidobacterium animalis subsp. lactis BLC1 is a probiotic bacterial strain originally developed by Sacco S.r.l. for use in functional foods, nutraceuticals, and pharmaceutical applications. It is currently being evaluated as a live biotherapeutic product (LBP) for the treatment of non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD). In clinical trials, such as those conducted by Amsterdam UMC, BLC1 is administered orally as part of a synbiotic cocktail—often in combination with other commensal bacteria like *Anaerobutyricum soehngenii* and *Akkermansia muciniphila*—to modulate the gut microbiome, reduce inflammation, and improve metabolic health.

Other names
Bifidobacterium animalis subsp. lactis strain BLC1B. lactis BLC1

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