Drug intelligence / Profile preview

Bifidobacterium bifidum BBi32

Development stage
Preclinical
Lead developer
Wecare Probiotics
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

**Bifidobacterium bifidum BBi32** is a specific strain of the species Bifidobacterium bifidum, a **Gram-positive, non-spore-forming, anaerobic actinobacterium** commonly used as a probiotic[3][1]. B. bifidum strains are widely recognized for their ability to colonize the gastrointestinal tract and confer health benefits such as suppression of pathogenic microorganisms, modulation of the immune system, enhancement of intestinal barrier function, and reduction of inflammation[3][1][5]. The BBi32 strain is presumed to share the hallmark features of its species, including strong **adhesion to intestinal cells, immune modulation, and the potential to ameliorate symptoms of gastrointestinal disorders** such as irritable bowel syndrome, large bowel dysfunctions, and inflammatory bowel conditions[3][7]. It may also possess mechanisms that protect the intestinal epithelium and contribute to establishing a balanced gut microbiota, especially in infants and individuals with disrupted microbiota[3][1][7]. While specific proprietary or clinical data for the BBi32 strain is not present in the available results, it is classified as a live probiotic bacterium with anticipated benefits similar to other clinically-used B. bifidum strains.

Brand names
Bifidobacterium bifidum BBi32
Other names
Bifidobacterium bifidum BBi32

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