Drug intelligence / Profile preview

bifidobacterium longum + lactobacillus acidophilus + enterococcus faecalis (Shanghai New Asiatic Pharmaceutical)

Development stage
Unknown
Lead developer
Shanghai New Asiatic Pharmaceutical
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bifidobacterium triplex live bacteria capsule is a live biotherapeutic product widely used in China for the treatment of intestinal dysbiosis and as an adjunct therapy for *Helicobacter pylori* eradication. It typically contains three live bacterial strains: *Bifidobacterium longum*, *Lactobacillus acidophilus*, and *Enterococcus faecalis*. The mechanism involves restoring the balance of the intestinal microbiota, inhibiting the growth of pathogenic bacteria through competitive exclusion and the production of organic acids, and modulating the host immune response. In clinical practice, it is frequently added to standard quadruple therapy for *H. pylori* to improve eradication rates and mitigate gastrointestinal side effects associated with antibiotic use.

Brand names
PeifeikangBifid
Other names
Bifidobacterium Triple Viable CapsulesBifidobacterium triplex live bacteria capsule双歧杆菌三联活菌胶囊

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