Drug intelligence / Profile preview

bifidobacterium longum + lactobacillus acidophilus + enterococcus faecalis (Shanghai Sine Pharmaceutical)

Development stage
Unknown
Lead developer
Shanghai Xinyi Bailuda Pharmaceutical
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bifidobacteria Triple Viable Capsule (marketed as Pefeikan) is a probiotic combination product containing live *Bifidobacterium longum*, *Lactobacillus acidophilus*, and *Enterococcus faecalis*. It is primarily used to treat intestinal dysbiosis and associated gastrointestinal disorders such as diarrhea, constipation, and abdominal distension. The mechanism involves the colonization of the intestinal tract with beneficial bacteria, which produce organic acids, lower intestinal pH, and inhibit the growth of pathogenic microorganisms. Recent clinical research, such as studies by Shanghai Sixth People's Hospital, explores its role in modulating the lung–gut axis to improve outcomes in conditions like pulmonary fibrosis by influencing systemic immune markers and microbiota composition.

Brand names
PefeikanBIFICO
Other names
Bifidobacteria Triple Viable CapsuleBifidobacterium Triple Viable CapsulePefeikangBifidobacterium, Lactobacillus and Enterococcus Triple Viable Capsules

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