Drug intelligence / Profile preview

bifidobacterium longum + lactobacillus plantarum + bifidobacterium infantis + lactobacillus reuteri

Development stage
Unknown
Lead developer
Shenzhen People's Hospital
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bifidobacterium longum + Lactobacillus plantarum + Bifidobacterium infantis + Lactobacillus reuteri is a combination of four specific strains of probiotic bacteria. Probiotics are live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. This combination is intended to support gastrointestinal health by modulating the gut microbiota. These bacteria work by colonizing the gut, where they can compete with pathogenic organisms for adhesion sites and nutrients, produce antimicrobial substances, and enhance the integrity of the intestinal barrier. Furthermore, they interact with the host's immune system, particularly the gut-associated lymphoid tissue, to modulate immune responses. Individual strains within this combination have been studied for various benefits; for example, *Bifidobacterium infantis* is noted for its role in the infant gut microbiome and reducing symptoms of Irritable Bowel Syndrome (IBS), *Lactobacillus plantarum* for supporting gut health and immune function, *Bifidobacterium longum* for producing lactic acid and supporting healthy cholesterol levels, and *Lactobacillus reuteri* for preventing infections and treating colic. While products exist that contain some of these strains in combination with others, a commercially available product containing this exact four-strain composition was not explicitly identified in the search results.

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