Drug intelligence / Profile preview

Bifidobacterium longum 35624 + Bifidobacterium longum 1714

Development stage
Unknown
Modality
Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bifidobacterium longum 35624 + Bifidobacterium longum 1714 is a dual-strain probiotic combination developed by Novonesis (formerly Precision Biotics) that targets the gut-brain axis. The product combines two specific strains of Bifidobacterium longum: strain 35624 (formerly classified as B. infantis 35624) and strain 1714. Strain 35624 is recognized for its anti-inflammatory properties and its ability to alleviate gastrointestinal symptoms such as abdominal pain and bloating, particularly in patients with irritable bowel syndrome (IBS). Strain 1714 is a psychobiotic that has been shown to modulate brain activity and reduce cortisol levels, helping to manage stress and anxiety. The combination is marketed for the management of IBS and associated psychological symptoms, and it has been investigated in clinical trials for its effects on fatigue and inflammatory markers in patients with ulcerative colitis.

Brand names
IBme DualGut-Brain ResetZenBiome Dual
Other names
B. longum 35624 + B. longum 1714Bifidobacterium longum 35624 and Bifidobacterium longum 1714
02

Targets

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