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bifidobacterium longum CECT7894
- Development stage
- Unknown
- Lead developer
- AB-BIOTICS
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
Bifidobacterium longum CECT7894 is a specific probiotic strain of the Bifidobacterium longum species. It is being investigated for its ability to regulate gut microbiota and alleviate functional constipation in infants and young children. As a live biotherapeutic, it works by colonizing the gastrointestinal tract, producing beneficial metabolites such as short-chain fatty acids, and improving bowel movement frequency and stool consistency. The strain was originally identified and developed by AB-Biotics and is being studied in clinical trials sponsored by institutions like Xinhua Hospital.
- Other names
- B. longum CECT7894
02
Targets
Farnesoid X receptor (FXR) and G protein-coupled bile acid receptor 1 (TGR5)
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