Drug intelligence / Profile preview

Bifidolin Plus

Development stage
Unknown
Lead developer
Orenda International
Modality
Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Bifidolin Plus is a combination herbal and probiotic dietary supplement developed by Orenda, primarily indicated for the restoration and maintenance of a healthy intestinal microbiome. The formulation contains the probiotic strain *Bifidobacterium animalis* subsp. *lactis* (often the BB-12 strain) and a root extract of *Inula helenium* (Elecampane). The probiotic component works by colonizing the gastrointestinal tract, competing with pathogenic microorganisms, and enhancing the intestinal barrier function. The *Inula helenium* extract provides a natural source of inulin, which acts as a prebiotic to stimulate the growth of beneficial bacteria, and contains sesquiterpene lactones that possess mild antimicrobial and anti-inflammatory properties. This product is typically used to manage dysbiosis, irritable bowel syndrome (IBS), and gastrointestinal disturbances associated with antibiotic use.

Brand names
Bifidolin Plus
02

Targets

TLR2 (Toll-like Receptor 2)NF-κB

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