bilastine

Bilastine is a potent, long-acting, second-generation antihistamine developed for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. It functions as a highly selective peripheral histamine H1 receptor antagonist. Notably, bilastine is non-sedating due to its minimal penetration of the blood-brain barrier and lacks significant affinity for other receptors, such as muscarinic, serotonergic, or adrenergic receptors. It is not metabolized by the liver's cytochrome P450 system, which minimizes the risk of drug-drug interactions. Developed by Faes Farma, it is widely approved in Europe, Canada, and Japan, though it is not currently FDA-approved in the United States.

Brand names

BilaxtenBilaskaBlextenIlaxtenNixarVilaxtenBilanoAntalerg

Other names

bilastinum