bimatoprost + brimonidine

Bimatoprost + brimonidine is a fixed-dose combination of two ophthalmic drugs used primarily to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Bimatoprost is a prostaglandin analog (specifically, a prostamide) that reduces intraocular pressure by increasing the outflow of aqueous humor through both the trabecular meshwork and uveoscleral pathways. Brimonidine is an alpha-2 adrenergic receptor agonist that lowers intraocular pressure by decreasing aqueous humor production and increasing uveoscleral outflow. The combination leverages complementary mechanisms to achieve greater reduction in eye pressure than either agent alone, making it useful for patients who require additional IOP lowering beyond monotherapy[1][2][5][6].

Other names

brimonidine + bimatoprost