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bimatoprost + hypromellose
- Development stage
- Unknown
- Lead developer
- Allergan
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
Bimatoprost + hypromellose is a combination of two ophthalmic agents used primarily for eye conditions. Bimatoprost is a synthetic prostaglandin analog that lowers intraocular pressure by increasing the outflow of aqueous humor through both the trabecular meshwork and uveoscleral pathways, making it effective in treating open-angle glaucoma and ocular hypertension. It can also promote eyelash growth in cases of hypotrichosis[1][3][5][7][8]. Hypromellose, also known as hydroxypropyl methylcellulose, acts as an ocular lubricant or artificial tear to relieve dryness and irritation caused by reduced tear flow or other eye diseases[2][4]. The combination may be used to manage elevated intraocular pressure while providing lubrication to reduce discomfort associated with dry eyes.
- Brand names
- Genteal MildGonakGoniosoftGonioviscIsopto TearsNature's TearsTearisolTears Again
- Other names
- hydroxypropyl methylcellulose (for hypromellose)artificial tears (for hypromellose)
02
Targets
PTGFR (Prostaglandin F2 alpha receptor)
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