Drug intelligence / Profile preview

Bimatoprost Implant System

Development stage
Phase 3
Lead developer
SpyGlass Pharma
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

The Bimatoprost Implant System (BIM-IOL System) is a long-acting, sustained-release drug delivery platform developed by SpyGlass Pharma for patients with open-angle glaucoma or ocular hypertension who are undergoing cataract surgery. The system integrates two non-bioerodible drug-eluting pads onto a standard hydrophobic acrylic intraocular lens (IOL). These pads are pre-loaded with bimatoprost, a prostaglandin analogue, and are designed to provide continuous therapeutic delivery for up to three years. By combining the drug delivery with a necessary cataract procedure, the system aims to improve patient compliance and provide stable intraocular pressure (IOP) control. The device is implanted into the capsular bag through a standard incision during phacoemulsification.

Other names
SpyGlass Bimatoprost ImplantSpyGlass IOL with BimatoprostSpyGlass Pharma Bimatoprost Implant
02

Targets

PTGFR (Prostaglandin F2 alpha receptor)

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