Bimin Mixture II

Bimin Mixture II is an herbal medicine primarily indicated for the treatment of allergic rhinitis. It is understood to be a specific formulation of Bimin Kang Mixture (BMK), which comprises 18 herbal ingredients. The therapeutic action of Bimin Mixture II involves modulating the NF-κB signaling pathway, reducing inflammatory cell infiltration, regulating mucosal immune balance, and decreasing airway hypersensitivity. Key active components, such as quercetin, kaempferol, and luteolin, contribute to these effects by interacting with various inflammatory targets, including the IL-1β protein receptor, CXCL2, CCL20, PTGS2 (COX-2), and CXCL8. Inhibition of COX-2 expression is considered crucial for minimizing airway inflammation in allergic rhinitis.

Other names

鼻敏合剂（II）Bimin Kang Mixture鼻敏合剂