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bimintongqiao decoction
- Development stage
- Unknown
- Lead developer
- Jiangsu Provincial Hospital of Traditional Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Bimintongqiao decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by the Jiangsu Province Hospital of Chinese Medicine for the treatment of allergic rhinitis. As a hospital-specific preparation, it is designed to address the TCM patterns of Qi deficiency and wind-cold invasion. Pharmacologically, the decoction exerts anti-allergic and immunomodulatory effects by regulating the balance between Th1 and Th2 immune responses. It has been shown to decrease the production of pro-inflammatory Th2 cytokines such as Interleukin-4 (IL-4) and Interleukin-5 (IL-5) while increasing Th1 cytokines like Interferon-gamma (IFN-γ). Additionally, it reduces serum levels of allergen-specific Immunoglobulin E (IgE) and inhibits the infiltration of eosinophils into the nasal mucosa, thereby alleviating symptoms such as sneezing, rhinorrhea, and nasal congestion.
- Other names
- Bimin Tongqiao TangBimin Tongqiao Decoction鼻敏通窍汤
02
Targets
IL-4 (Interleukin 4)IL-5 (Interleukin 5)IgE (Immunoglobulin E)
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